February 1, 2023

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Dr. Ernst Von Schwarz: Study Shows Promising Benefit of Mesenchymal Stem Cell Injection in Critically Ill COVID-19 Patients

Press Release

up-to-date: Sep 24, 2021 14:40 PDT

COVID-19 infections characterize a existence-threatening problem secondary to respiratory and multi-organ failure as a consequence of a systemic inflammatory response. Stem mobile remedy might ameliorate the fundamental consequences probably secondary to anti- inflammatory houses.

“Our paper, just revealed, specials with one thing new and incredibly promising in medication,” states Dr. Ernst von Schwarz. “We utilized stem cell therapy, which is now not Food and drug administration accredited, in the type of acellular stem mobile — derived bioactive molecules, which we injected into critically sick individuals with COVID 19, who had been admitted to a big metropolitan hospital’s intense treatment device.” 

The analyze was built as a randomized, double blind, placebo managed analyze. Neither the investigators nor the sufferers knew whether they obtained a placebo saline injection or a stem mobile derived molecule product. 

“We don’t presently have a immediate treatment method for COVID – 19, and sufferers who require hospitalization are critically unwell,” claims Dr. von Schwarz. “Stem cells in normal have selected qualities, like anti-inflammatory properties, which theoretically at least can aid mitigate inflammatory responses. These clients stop up in the clinic or in an intense care unit thanks to respiratory distress. They may possibly be put on a ventilator, with often a lethal end result. So you will find genuinely not considerably to reduce to take into account offering one thing in addition to the conventional regimen remedy.” 

“This was a pilot phase review, so a relatively smaller quantity of 26 people were associated, 50 percent assigned to a placebo team and the other 50 percent assigned to the treatment group. We administered just a solitary injection of placebo or the stem cell derived molecules intravenously. We then analyzed for tolerability, basic safety and medical outcomes.” 

“All the injections were being pretty very well tolerated,” states Dr. von Schwarz. “There were no important aspect results observed. In the placebo group, 6 out of 13 individuals died, which equals a 46.1 % dying price, compared to just a single individual in the treatment team who died, representing a 7.7 p.c loss of life fee. In doing a very simple statistical investigation, this is a extremely significant variance in between people who gained the placebo and patients who gained the stem mobile product. The hypothesis is that the decreased mortality in this modest research is because of to anti-inflammatory results of the stem mobile injection.”

“As a final result of this study, stem cells for compassionate use are revealed to be a risk-free and promising therapeutic solution for the cure of critically ill individuals with COVID-19. Even more massive scale scientific tests, even so, are needed to verify these very appealing preliminary benefits.”

Speak to: Gary Grasso, Physicians PR –  [email protected]

Supply: Dr. Ernst von Schwarz